SWISSE - Clinical studies

Clinical studies and quotes verifying the benefits of multivitamins

"Every adult should take a multivitamin daily."

Dr Kathleen M Fairfield MD Dr.Ph, and Dr Robert H Fletcher MD MSc, "Vitamins For Chronic Disease prevention in Adults: Clinical Applications" Journal of American Medical Association, Volume 287, No. 23, June 19 , 2002; 3127. Based on review of clinical studies1 between 1966 and 2002 regarding link of vitamin intake and disease.

"Regular use of a multivitamin was associated with a 34% reduction in heart attack risk in women and 21% in men."

Holmquist C, Larsson S, Wolk A, et al., "Multivitamin supplements are inversely associated with risk of myocardial infarction in men and women- Stockholm Heart Epidemiology Program (SHEEP)," Journal of Nutrition, 2003;133:2650-2654.

"Multivitamin Antioxidant combination decreases damage to chromosomes. The percentage of cells with "chromosome aberrations" decreased by 57% with supplementation. The most significant effect was in smokers, who had only 0.12 percent chromosome damage, compared with 0.81 percent in smokers who took placebos."

Dusinska M, Kazimirova A, Barancokova M, et al., Nutritional supplementation with antioxidants decreases chromosomal damage in humans," Mutagenesis, 2003;18:371-376.

"A well-balanced multivitamin is better than several single supplements."

Nicola Reavley, leading scientist, author: "The New Encyclopedia of Vitamins, Minerals, Supplements and Herbs" Bookman Press

"We were able to identify significant cost savings based on improved immune function and a reduction in the relative risk of coronary artery disease through providing a daily multivitamin to the 65 and over population."

Dr. Allen Dobson, Multivitamins Public Health, Exploring The Evidence, October 2003, Washington DC.

"Do your best to obtain proper nutrition, sufficient exercise and adequate rest."

'Measures to avoid getting sick', World Health Organisation (WHO), Report on Infectious Diseases, December 2000.

"Taking Aspirin has been associated with increased loses of vitamin C, iron and folic acid. A multivitamin can assist in minimising the side effects."

Coffey G, Wilson CWM. Ascorbic acid deficiency and aspirin induced haematemesis. British Medical Journal 1975;1:208

"Copper may enhance the anti-inflammatory effect of NSAIDs."

'Sorenson JRJ. Copper chelates as possible as possible active forms of the antiarthritic agents. Journal of Medicinal Chem 1976;19:135-148.

"Double blind clinical trial in Oxford, UK, shows 50mg of Vitamin B6 per day to have significant beneficial effect on reducing PMT symptoms such as depression, irritability and tiredness."

Doll H; Brown S; Thurston A; Vessey M. Pyridoxine (vitamin B6) and the premenstrual syndrome: a randomised crossover trial. JR Col General Practice , 1 989 Sept, 39:326, 364-8

"12 clinical trails involving 1114 people shows 500mcg Folic Acid to reduce blood homocysteine & may reduce the risk of coronary heart disease."

Lowering blood homocysteine with folic acid based supplements:
Meta-analysis of randomised trials. Homocysteine Lowering Trialists Collaboration. British Medical Journal 1998, Mar, 316:7135, 894-8

"A clinical study of 730 women and men followed up for a 20 year period showed that higher blood levels of Vitamin C is linked to half the risk of death from stroke."

Gale CR; Martyn CN; Winter PD; Cooper C - Vitamin C and risk of death from stroke and coronary heart disease in cohort of elderly people. British Medical Journal, 1995 Jun, 310:6994, 1563-6.

"Vitamin B12 deficiency may cause pernicious anemia which may lead to blindness, insanity and death. Low levels could contribute to chromosome damage in white blood cells."

Lindenbaum JE, et al. New England Journal Of Medicine, 1988;318:1720-28. Fenech MF; Dreosti IE; Rinaldi JR. Folate, Vitamin, B12, homocysteince status and chromosome damage rate in lymphocytes of older men. Carcinogenesis, 1997 Jul, 18:7, 1329-36

"Taking high doses of vitamin E may lead to peroxidation, increased risk of bleeding, diarrhea, abdominal pain, fatigue, reduced resistance to bacterial infection, raised blood pressure, a decline in vitamin C in the blood."

Brown KM; Morrise PC; Duthie GG Erythrocyte vitamin E and plasmaascorbate concentrations in relation to erythrocyte peroxidation in relation to smokers and non smokers: Dose response to vitamin E supplementation. American Journal of Clinical Nutrition, 1997, Feb, 65:2, 496-502

"Safety and efficacy are crucial but separate issues for vitamins and mineral supplements. Misinterpretation of "safe and adequate" to mean "safety limit" would impose restrictions on vitamin and mineral intakes that are not needed to ensure safety. The margin of safety between the usual dietary intake and the intake that would produce adverse effects varies greatly among the different nutrients. Very high intakes of vitamin A and D, niacin, pyridoxine, and selenium have produced adverse effects. Many widely discussed putative adverse effects of vitamin C, vitamin E, and trivalent chromium have little factual basis. There is no evidence of adverse effects from beta-carotene supplements except in current heavy smokers."

Clin Nutr 1997;66:427-37. John N Hathcock

"Micronutrients act in concert, like an orchestra. If only the tuba player and violinist show up, it doesn't sound so good. However, if the whole orchestra is there, you'll have a top chance of a great show."

Dr John Tickell MD, leading medical speaker, author and Stress Management Expert

		Clinical studies	Clinically Tested. Proven Benefits. "You'll feel better on Swisse!"
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